Total Serum Testosterone Level in Obese Patients with Type -2 Diabetes Mellitus

Both obesity and type 2 diabetes mellitus (T2DM) are independently associated with reduced serum testosterone. The additive effect of T2DM on reducing testosterone levels need to be investigated. Their combined effects may place obese patients at higher risk decreased the increased morbidity mortality. aim this study was screen for biochemical hypogonadism regardless presence overt clinical symptoms consider replacement therapy. 152 adult male aged 40 68 years were recruited through simple random sampling. participants grouped based their BMI into lean (n=48); overweight (n=57), (n=37) morbidly (n=11). Total (TST), waist circumference (WC) measured in all luteinizing hormone (LH) 103 them. Low TST defined as TST<9nmol/L normal range LH 1.7-11.2mIU/ml. Mean 15.61± 6.0 nmol/l. significantly lower groups compared group (P=0.003 0.015 respectively). negatively correlated (r= -0.29, P<0.001) WC -0.21, P<0.009). Overall, 19.7% had low TST. prevalence from 14.9% lean, 21.1% overweight, 21.6% obese, 27.3% patients, (P=0.74). inappropriately 95% (19/20) Obese a patients. WC. Therefore, screening deficiency should considered.